Design 4 Drupal, Boston will be held at the Massachusetts Institute of Technology in the fabulous Stata Center at 32 Vassar St, Cambridge, MA

Public transportation to is the way to go. The MIT area is easily accessible from the Red Line as well as several bus lines. There's also a few public parking garages right near by.

There's some pretty nice hotels in walking distance to MIT Stata Center including the Kendall Hotel, Cambridge Marriott, Residence Inn, and lots of "Airbnbs."